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De Simone et al., 2023

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Description & Pharmacodynamics Epithalon is derived from epithalamin, a natural peptide produced in the pineal gland

8.2, Pharsight Corporation, California, USA) to calculate the pharmacokinetic parameters for each subject, including the bracketed peak concentration (C max ), the area under the blood concentration time curve (AUC 0t and AUC 0 ), the time to peak (T max ), the elimination half-life (t 1/2 ), and the elimination rate constant ()