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Nat Rev Immunol 13 , 922 (2013)

10.1038/sj.mp.4001362 134

The median CA 19-9 level, a prognostic marker commonly used to reflect disease burden and PDAC aggressiveness, was similar between groups at diagnosis, although it trended towards a higher value in the high glucose group (2439.5 U/mL high glucose vs 1294.5 U/mL normal glucose, P =0.224)

Diets enriched with EVOO significantly reduced clinical and histological damage, decreased mortality by about 50%, and improved cytokine profiles, including maintaining TNF- near control levels and increasing IL-10, while downregulating COX-2 and iNOS

Purified proteins were re-suspended in buffer (250 mM HEPES, 8 M urea, 0.1% SDS, pH 7.5) and replaced with buffer I (25 mM HEPES, 1 M urea, pH 7.5) three times in an ultrafiltration centrifugal tube (Merck, Amicon Ultra-0.5 mL, 10 KDa)