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Innate immune cells In the early stages of tissue injury, neutrophil influx is triggered by inflammation, but excessive recruitment of neutrophils can lead to an exaggerated inflammatory response

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For assessment of the intracellular metabolome the remaining supernatants were removed, the fungal biofilm was washed with ice-cold PBS, scraped, collected in a 50 mL tube, and centrifuged at 10,000 g and 4 C for 5 min

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It was found in the postmortem AD brain that there was an increase in the light chain of SLC7A11 [62], and a similar increase was observed in an AD mouse model [63]which is consistent with our current findings