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NADs ability to reduce inflammation, increase DNA repair and improve energy, makes it just as essential as hormone replacement to improve longevity

Weight loss is complex, and any observed weight reduction is likely due to healthier diet and increased physical activity

It modulates the nitric oxide system

Patient-reported outcomes will be important to demonstrate to regulators that many people with T1D can and want to benefit from islet cell replacement therapy, and we need established, systemic methods in place to take the T1D communitys opinions into account

Acknowledgments The authors would like to express their sincere appreciation to Clive Chen Clinic, Taichung, Taiwan, and the Department of Neurosurgery, Yuan Rung Hospital, for their valuable support and assistance in the completion of this study