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In a randomized controlled trial in 72 subjects with migraine, 50,000 IU (1,250 mcg) of oral vitamin D every two weeks plus a daily multi-strain probiotic providing 450 billion colony forming units (CFUs) for 12 weeks reduced the frequency and severity of migraines (Tirani 2024)

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Vitamin B12 is an essential nutrient which is required by the body to make red blood cells and maintain a healthy nervous system

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