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Supporting energy delivery to the brain, mitochondrial function and reducing inflammation is essential Mitochondria are susceptible to oxidative stress and therefore including antioxidants such as N-acetyl cysteine, CoQ10, glutathione and alpha lipoic acid are important for protection of the mitochondria

These subsequent injuries involve the disturbance of the blood-brain barrier (BBB), excitotoxicity induced by glutamate, oxidative stress, and neuroinflammation, all of which can develop in a time-dependent manner following the initial mechanical injury (Chiu et al., 2016)

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Song X, Zhao Y, Cai Q et al (2013) Association of the glutathione S-transferases M1 and T1 polymorphism with male infertility: a meta-analysis

Orozco-Cortes PC, Flores-Ortiz CM, Hernandez-Portilla LB, Vazquez Medrano J, Rodriguez-Pena ON (2023) Molecular docking and in vitro studies of ochratoxin A (OTA) biodetoxification testing three endopeptidases