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The candidate is now in Phase II clinical trials, representing a significant reduction in the traditional drug discovery timeline [242]

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

test compounds were evaluated in the human and rat liver microsome assay described above along with midazolam as a positive control and with no NADPH in reaction system as a negative control

the mitigation column below is deliberately conservative, and the recurring theme is that technique and consistency solve more problems than dose changes

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