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The systematic name of this enzyme class is gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)

Glutathione (GSH) was involved in stomatal closure induced by ABA, as its presence in guard cells regulated ABA signaling in the Arabidopsis cad2-1 mutant (Okuma et al

We proposed this as a novel asthma treatment strategy to complement current asthma therapeutics which target inflammation ( Our studies in the GGT enu1 mouse also demonstrated the value of this animal model in defining a biologic role for extracellular pools of glutathione in combating oxidant stress derived from inflammation

and Grant ME 1567/9-1 to A.J.M.)