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According to the studys findings, b12 group experienced a minor improvement in anxiety and depression when compared to the placebo group B12 shots are usually administered into an area of muscle, sites include the upper arm, buttocks and abdomen The injection is given into a muscle (known as an intramuscular injection)

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A large clinical study in South Korea of 629 patients who underwent spinal fusion also found that post-operative patient satisfaction was around 71%, with unsatisfied patients reporting the persistence of chronic pain after the surgery (Kong et al., 2010)

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