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Gene products at the transcriptional and post-transcriptional levels, in addition to the mutation itself, can reveal the underlying pathophysiological processes of PD (Tnges et al., 2022)

[109] Some epidemiological studies have suggested possible increased risks for specific congenital malformations, particularly cardiac defects and orofacial clefts, though these findings have not been consistently replicated across all research populations

For instance, physical changes like arthritis may restrict motion, which in turn may lead to a decline in assessment [9]

Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53

doi: 10.1016/j.clnu.2011.02.009 65