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Lentivirus-mediated overexpression or silencing of aquaporin 1 affects the proliferation, migration and invasion of TNF--stimulated rheumatoid arthritis fibroblast-like synoviocytes by wnt/-catenin signaling pathway

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Interestingly, gene silencing potency was closely related with p K a value: ionizable lipids with p K a between 6.2 and 6.5 had the lowest ED 50