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Satyanarayana T, Kunze G, editors

Planta 186: 600-608

doi: 10.3390/nu13051739

One mechanism through which chronic drug use leads to the impaired regulation of drug seeking (relapse) is an enduring imbalance in how non-synaptic glial glutamate regulates synaptic glutamate transmission at prefrontal-to-accumbens synapses (that is, a loss of glutamate homeostasis)