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Setting realistic expectations prevents premature protocol modifications that could compromise study validity

2 Crosstalk among RA, gut microbiota, and immune system The gut microbiota has gained more and more accentuated attention from specialists as a key contributor to the development and progression of RA ( Figure 1 )

10.1016/j.biopha.2020.111191 132 WesthoffJ

Atherosclerosis 218:4452 Kukongviriyapan U, Sompamit K, Pannangpetch P, Kukongviriyapan V, Donpunha W (2012) Preventive and therapeutic effects of quercetin on lipopolysaccharide-induced oxidative stress and vascular dysfunction in mice

By modulating both inhibitory and excitatory neurotransmitter systems, NAS maintain the stability of neural networks