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Since CBD is known as an agonist of 5-HT 1A (Russo et al., 2005), it would technically mediate similar effects as 5-carboxyamidotryptamine (5-CT) and 8-OH-DPAT (a 5HT 1 serotonergic agonists) in the previous experiment (Figure 1)

N1IC tumors harbored quiescent astrocyte-like transformed cell populations while p53 tumors were predominantly comprised of proliferating progenitor-like cell states