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J Agric Food Chem 56:90649071

Intrahepatic CD4 + T cells are important for antitumor surveillance in NAFLD

Therefore, icariin and icaritin promote the infiltration of immune cells, inhibit various immune checkpoints, reduce the levels of inflammatory cytokines and enhance anti-cancer immunity

These data pointed to the possibility that the cooperative engagement of CRBN might depend on contacts made outside of the 10 radius included in the DMS screen