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Similarly, chronic administration of 56.4 mol/kg SF for 15 days alleviated anxiety-like behavior and produced antidepressant effects in neuropathic mice, as evidenced by behavioral tests in neuropathic mice (133)

This effect of ER activation is likely mediated by modulation of activity of a pathway projecting from the VMH to serotonergic neurons in the dorsal raphe nucleus a pathway important for the regulation of brown fat thermogenesis (BAT) and locomotor activity (83)

Development and optimization of an in vitro release assay for evaluation of liposomal irinotecan formulation

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Research suggests that targeting ERR with DN200434 could overcome resistance to sorafenib by triggering ferroptosis, highlighting the potential role of estrogen-related receptors in regulating ferroptosis in cancer cells [98]