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The FSP1/CoQ10/NADPH system protects cells from ferroptosis in a manner independent of the GPX4 axis by inhibiting lipid peroxidation and ferroptosis through the NAD(P)H-dependent reduction of CoQ10 to ubiquinol (CoQH 2 ) [23]

Glutathione (GSH) is a small protein molecule composed of three amino acids: cysteine, glutamate, and glycine

The psychiatric disorders involving impairment in cognition and behavior include Schizophrenia spectrum disorder (SSD), autism spectrum disorder (ASD), Parkinsons disease, and Alzheimers disease ( 2+ influx, and gene expression ( The retina is considered an extension of the brain and has been linked to many neurological disorders ( Schizophrenia spectrum disorder (SSD) and autism spectrum disorder (ASD) are neurodevelopmental disorders associated with social and communication impairment and cognitive dysfunction

Numerous studies have now characterized the PD gut microbiome, consistently finding dysbiosis relative to neurologically normal controls [150]