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The mitochondrial enzyme ALA synthase (ALAS) initiates the rate-limiting condensation of succinyl-coenzyme A and glycine to form 5-aminolevulinate (ALA) 26

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Rather than relying on a single viewpoint, the research blends the bottom-up view (building the market from individual companies and segments upward) with the top-down view (sizing the total market and working down to the segments)