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Minoxidil acts as a potassium channel opener and adenosine receptor agonist, while AHK-Cu targets VEGF, TGF-1, and collagen synthesis

It forms a complex with TFE3 and TRIM28 that enhances H3K4me3, an activating mark, at the promoters of ATG5, LC3B , and GABARAPL1 , thus leading to their transcriptional upregulation

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