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Restlessness at night in an older dog is often linked to the cognitive changes of aging the canine version of sundowning

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For RUBISCO_S , the highest expression was observed in the 15th day sample of IISR Thevam, with a 749.6-fold increase, followed by the 15th day sample of Panniyur 1, which showed a 418.76-fold increase

Results build gradually over weeks with consistent application, making them less dramatic but still valuable for visible improvement

Zamanian et al., 2012) that may be beneficial in microbial infection but can be detrimental in neurodegenerative disease (Sofroniew, 2014)