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2) Analysis of pharmacokinetic profiles and tissue distribution in both normal rats and rats with cerebral ischemia-reperfusion injury (CIRI) via UPLC-MS/MS

In disease states, BBB breakdown and dysfunction lead to leakages of inappropriate as well as harmful blood components into the CNS, cellular infiltration, and aberrant transport and clearance of molecules

In these cases, IV or injectable delivery is not optional it is medically necessary

ISSN 0014-2956

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