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Glodde N, Bald T, van den Boorn-Konijnenberg D, Nakamura K, ODonnell JS, Szczepanski S, Brandes M, Eickhoff S, Das I, Shridhar N, et al

When skin has lost its elasticity and you stretch it tight (remove all the excess skin), the skin once healed will continue to stretch out over time and become thinner and thinner

the permeation enhancer is selected from sodium caprylate, sodium caprate, sodium laurate, sucrose laurate, sucrose stearate, sodium stearate, EDTA, polyacrylic acid, and N-[8-(2-hydroxybenzoyl)amino]caprylate or a pharmaceutically acceptable salt thereof (particularly sodium N-[8-(2-hydroxybenzoyl)amino]caprylate)

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