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To achieve a power of 80% at = 0.05, we estimated that a minimum of 16 cases and 32 controls would be required

Watson K, Nasca C, Aasly L, McEwen B, Rasgon N (2018) Insulin resistance, an unmasked culprit in depressive disorders: promises for interventions

In contrast, no significant association was found for TPOAb positivity (60)

Psychosom Med 66:276282 Veronese N, Stubbs B, Solmi M, Ajnakina O, Carvalho AF, Maggi S (2018) Acetyl-l-carnitine supplementation and the treatment of depressive symptoms: a systematic review and meta-analysis

Skin reactions: Skin rash and nausea have been reported with oral supplementation [29]