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In particular, EPI can lead to a lack of IF and consequent hypocobalaminaemia [35], whereas alimentary lymphoma and chronic intestinal inflammation are responsible for impaired nutrient uptake [30,37]

People prefer subcutaneous injection when administering small amounts of medicines or vitamins, such as vitamin B12, at home

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Conclusions In summary, our study evidenced that AT-specific B12 deficiency significantly dysregulated AT lipid metabolism and inflammation, thereby promoting dyslipidemia and worsening obesity-related complications that could underlie the development of IR and cardiometabolic risk