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In the phase 2 dose-finding trial involving 706 participants, nausea rates varied dramatically by dose

1 * Significant, clinically proven reduction in HBV recurrence and demonstrated survival benefit 4 Two adverse reactions were observed in clinical trial subjects who received HepaGam B hypotension and nausea 1 No thimerosol or mercury-derived preservatives 1 SELECTED IMPORTANT SAFETY INFORMATION Individuals known to have severe, potentially life-threatening reaction to human globulin preparations should not receive HepaGam B or any other immune globulin (human)

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If the altimeter setting is above 29.92", the air density is a little higher that normal so the density altitude will be slightly less (see my web article on how to calculate that too)