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In addition, GFAP / Vim / mice show an altered response of astrocytes in neurodegenerative diseases, including limited presence of astrocyte processes in the direct vicinity of -amyloid plaques, impaired cytokine production, aberrant astrocytemicroglia interactions and faster progression of both AD and Batten disease in the respective mouse models 127,197,406

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Thirdly, the co-existing antioxidants and heme-containing agents other than catalase in dietary constituents or body fluids

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