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Indeed, several studies have found that adherence to polyphenol-rich diets is associated with a lower risk of developing PD and with better clinical outcomes in PD patients (9)

10.1016/j.lf10.1016/j.lfs.2011.01.015 37 IlicS.DrmicD.ZarkovicK.KolencD.CoricM.BrcicL.et al (2010)

Multiple other cell types throughout the central and peripheral autonomic nervous system are also involved, probably from early disease onwards

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LCMS (ES, m/z) calculated for C 22 H 28 N 5 O 2 + [(M + H) + ] 394.2, observed 394.2 Synthesis of tert -Butyl 4-(1-(trifluoromethyl)-[1,2,4] triazolo[4,3- a ]quinolin-7-yl)piperazine-1-carboxylate (5d) tert a Intermediate 4d was treated with 1-Boc-piperazine according to general procedure 5a-5d