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The assembly/disassembly of the FeS-Trx1 dimer fine tunes the activity of IRP1, a main regulator of iron homeostasis acting on the posttranslational level [13-15]

For example, C16-carnitine (10 M) may impair mitochondrial function in rat ventricular myocytes by accelerating ROS production and increasing the probability of mitochondrial permeability transition pore (mPTP) opening, whereas low concentrations (1 and 5 M) of C16-carnitine lightly hyperpolarize the m but do not open the mPTP [293]

The Growing Challenge of Test Interpretation Primary care physicians increasingly encounter patients who present with laboratory results obtained independently through commercial testing services

Schindelin H