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ScienceDirect , Scientific Reports , vol

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV

Kerr et al, 2012

As mentioned earlier, sirtuins can only perform their functions if NAD+ is present, which means, without the coenzyme, its nearly impossible to lead a healthy and happy life