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Mo Med (2020) 117:5368

In our previous study, we found that chemical inhibition of EGFR utilizing Canertinib, dramatically reduced hepatocyte steatosis, liver injury, and fibrosis, in a murine fast-food diet (FFD) model, indicating a potential role for EGFR in regulating NAFLD

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This indicates that Munc18-1 bound to the t-SNARE complex (Dawidowski and Cafiso, 2016) interacts with VAMP2 and still stimulates SNARE complex assembly (Shen et al., 2007