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anti-Flag, Sigma (F1804), for immunoblotting and immunofluorescence staining

Future research should focus on personalized antioxidant therapy guided by biomarker profiling to optimize clinical outcomes

The ubiquitin ligase STIP1 homology and U-box containing protein 1 (STUB1) ubiquitinates lysine 63 (K63), which then binds and degrades HIF1A in the lysosome, in conjunction with CMA proteins (111,112)