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Dubyk K, Borisova T, Paliienko K, Krisanova N, Isaiev M, Alekseev S, et al

It is effective, well-tolerated, extensively studied, and produces broad-spectrum improvements that benefit nearly every patient profile

At the same time, IL-6 and TNF- secreted by TAMs (tumor-associated macrophages) promote ROS accumulation through NOX2 activation, forming a vicious cycle of oxidative stress-ferroptosis (178)