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We found that during COVID-19 infection, differential metabolism drives lung ECs towards senescence and towards acquiring a SASP phenotype, leading to secretion of pro-inflammatory cytokines, reduced HLA class 2 mediated immunosurveillance, and increased HLA class 1 machinery

The derivatives of PTER showed antioxidant and inhibitory activity against the aggregation of -amyloid plaques, as well as cholinesterase inhibition, which would be useful in the treatment of patients with AD (Li Y

Long chain acyl-CoA synthetase 6 facilitates the local distribution of di-docosahexaenoic acid- and ultra-long-chain-PUFA-containing phospholipids in the retina to support normal visual function in mice

Comparable or better GI tolerability vs semaglutide alone in SURPASS-2