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El factor intrnseco (FI) es una glicoprotena secretada por las clulas parietales de la mucosa gstrica que tiene la funcin de unirse a la vitamina B12 una vez sta se ha desprendido de las protenas R, otorgndole resistencia a las proteasas gstricas y pancreticas, formando un complejo B12+factor intrnseco que se conoce como complejo de Castle

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Infliximab for induction and maintenance therapy for ulcerative colitis

The gas lines were cleaned separately with isopropyl alcohol (90%) and autoclaved (121 C, 15 min)

Notably, it is difficult to calculate an accurate FDR using the entrapment strategy given that it is unlikely to know the exact number of phosphopeptides in the human sub-library that is not present in the sample