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Reduced numbers of CB 1 receptors in the striatum is an important pathogenic factor in Huntingtons disease [44]

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The answer is no, but some people may feel like it does not look aesthetically pleasing, which is why such treatments are available

doi: 10.1016/j.neurobiolaging.2013.11.001 251 BraakHSastreMBohlJREde VosRAITrediciKD

An excessive shift in the balance would generate reductive stress leading to the protein aggregates and proteotoxicity as was reported in myocardium (Rajasekaran et al