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This process of rapid glucose uptake and metabolism culminates in an elevation of intracellular ATP, and an increase in the ATP/ADP ratio, and leads to closure of ATP-sensitive potassium channels, the depolarization of the cell membrane, and the opening of voltage-dependent calcium channels (VDCC), thereby activating a series of factors responsible for insulin secretion and the lowering of blood glucose concentrations [52]

Lide DR (ed.) (1991) CRC Handbook of Chemistry and Physics, 72nd Ed., Boca Raton, FL, CRC Press

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Other Ingredients : Besides the proprietary blends of the compounds mentioned above, the formula also contains plant enzymes (cellulase and peptidase), and HPMC (vegetarian capsule), as well as high-potency vitamin C