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By inhibiting epigenetic enzymes like DNMTs, compounds such as curcumin and apigenin reduce CpG hypermethylation in the NRF2 promoter, leading to elevated NRF2 levels and offering potential therapeutic benefits for diseases associated with oxidative stress [35, 149]

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Mechanism 3: 5-alpha Reductase Inhibition Preliminary data suggests GHK-Cu may inhibit 5-alpha reductase, the enzyme that converts testosterone to DHT the primary driver of androgenetic alopecia

The samples were sealed with a 1:1:1 vaseline lanolin paraffin mixture or vaseline and then imaged using the N-STORM setup with an iXon DU-897E electron-multiplying charge-coupled device camera (Andor)

In the last 100 years alone, there have been four major influenza pandemics and multiple epidemics, including the Spanish flu in 1918, with an estimated 1750 million deaths worldwide 3 , as well as the Asian and Hong Kong flu in 1957/58 and 1968/69 with one to four million deaths worldwide 4