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Austin J Med Oncol

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Pharmacol Ther 239:108277

Recently, new gene-editing strategies have been developed that enable high rates of homology-directed repair (HDR) of gene cassettes into specific genomic loci 4648

Isocitrate dehydrogenases (IDH) IDH also facilitates the generation of NADPH from NADP + by catalyzing the oxidative decarboxylation of isocitrate to -ketoglutarate (-KG) for TCA cycle