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RA-FLSs have tumor cell-like anti-apoptotic characteristics, and inhibition of their proliferation and migration has been the focus of attention in RA therapy

USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice

KDM5B knockdown in breast cancer cells activated the AMPK protein, reduced the level of lipid metabolism, and inhibited the epithelial-mesenchymal transition (EMT), and reduced their growth and migration ability, revealing novel theoretical evidence for the clinical regulation of tumor metabolism by targeting related genes

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doi: 10.1021/bi902022n 12 LevringTBHansenAKNielsenBLKongsbakMvon EssenMRWoetmannAet al