Expression of the transgenes in transduced 293T cells was confirmed by ELISA (GM-CSF, IFN-a) and flow cytometry analyses (tWT1)
induces a decrease of hepatic GSH." So alcohol consumption leads to a depletion of glutathione levels in the liver where, ironically, glutathione is made and can lead to liver damage

Water, Butylene Glycol, Caprylic/Capric Triglyceride, Beeswax, Niacinamide, Cetearyl Alcohol, Isononyl Isononanoate, Arachidyl Alcohol, 1,2-Hexanediol, Polyglyceryl-3 Methylglucose Distearate, Behenyl Alcohol, Glyceryl Stearate, Betaine, Arachidyl Glucoside, Cetearyl Olivate, Arginine, Carbomer, Sorbitan Olivate, Allantoin, Glycerin, Panthenol, Tocopherol, Xanthan Gum, Glutathione (600ppm), Dipotassium Glycyrrhizate, Ethylhexylglycerin, Disodium EDTA, Sodium Hyaluronate, Glucose, Multi-plant extracts (Mallow, Melissa, Yarrow, Veronica, Peppermint, Primrose), Ceramide NP, Hydrogenated Lecithin, Polyglyceryl-10 Stearate, Sodium Hydroxide, Sodium Ascorbyl Phosphate, Biotin, Folic Acid, Pyridoxine, Cyanocobalamin, Linoleic Acid, Riboflavin, Beta-Carotene, Thiamine HCl, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Fragrance

The unique pH-responsive nature of mNiO enables it to degrade and release Ni 2+ ions specifically in the acidic tumor microenvironment (TME)
A.SarhanO.et al (2023a)