foxo4-dri vs gdf-11 Structural basis for potency differences between GDF8 and GDF11 | BMC Biology The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell FOXO4 DRI alleviates age related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice PMC Deficiency of GDF 11 Accelerates TAC Induced Heart Failure by Impairing Cardiac Angiogenesis JACC: Basic to Translational Science
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