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The introduction to this cluster describes the thiol as the chemical reason glutathione participates in the reactions the literature describes

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Korean J Parasitol 59:189225

FIGURE 6 Activation of Adaptive Stress Responses by AQ-QI and DEAQ-QI and Effects of GSTP1 The stress responses induced by AQ-QI and DEAQ-QI exposure were measured with a high-content image-based BAC-GFP stress responses reporter assay for oxidative stress, ER stress, DNA damage stress and inflammatory stress (Wink et al., 2014, 2017)

We deployed network pharmacology to systematically map potential targets and biological pathways of Rg1, while developing interconnected drug-target-disease networks, for a purpose of better understanding molecular multi-target actions