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found that icariin (ICA), an active ingredient extracted from Epimedium, could prevent ROS production and mitochondrial dysfunction caused by iron overload in vivo and vitro osteoporosis model, although the authors attributed this effect to the fact that ICA could inhibit osteoblast apoptosis (68)

A UPLC/MS-based metabolomics study was employed to evaluate urinary biomarkers of hepatotoxicity in rats dosed with known hepatotoxins including APAP (Kumar et al

Funding This study was supported by grants from VIEP-BUAP-2019 given to IDL

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