glutathione reduced state Disulfide - an overview Glutathione and peroxisome redox homeostasis

Hum Mol Genet 23:782795

We show here that glutathione is a reservoir for synaptic glutamate, the excitatory neurotransmitter in the central nervous system

Besides, mitochondrial alterations in the functional regulation, energy metabolism and genetic stability accompany the aging process, and there has been a lot of evidence suggesting that oxidative stress and inflammation, both of which are associated with mitochondrial dysfunction, are predisposing factors of aging

doi: 10.3390/ijms221910777 182 KimHJJungYSJungYJKimOHOhBC

doi:10.1155/2012/190930, PMID: 22934169 Kang PT, Zhang L, Chen CL, Chen J, Green KB, Chen YR (2012) Protein thiyl radical mediates S -glutathionylation of complex I