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Topology optimization utilizes computational modeling to design graded lattice structures that are strong in the center but flexible and porous peripherally to mimic real bone behavior and reduce stress on the spine Robotic-assisted surgery and Navigation Robotics and navigation assistance have been increasingly integrated into orthopedic spine surgery over the past couple of decades

10.1136/bmj.j831 BMJ

Cancer cells lacking blood circulation expanded 12 mm 3 in diameter and afterward halted, but when put in a location where angiogenesis was feasible, they expanded to more than 2 mm 3

In this technique and very fine needle is used to install a small drop at multiple sites with in an area so as to spread the dose of medication evenly and to reduce the chance of side effects