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In the context of autoimmunity, the most relevant are those that influence T-cell differentiation, cytokine production, inflammatory signaling pathways, and immune cell communication

Metabolic reprogramming agents slow down the development of antibiotic resistance -lactam antibiotics and -lactamase inhibitors are increasingly used simultaneously (i.e., as combination therapy) to treat infections caused by pathogens that express -lactamase 90

doi: 10.1016/j.tins.2013.01.005 193

The PK/PD model was an indirect response model with MRI-PDFF reduction by the predicted drug concentration

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