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as such, dietary supplementation of choline is necessary

Figure 1: Changes in body weight from baseline to the end of treatment at week 26 associated with the trial product estimand, in the randomly assigned treatment groups administered either 0.3 mg of cagrilintide, 0.6 mg of cagrilintide, 1.2 mg of cagrilintide, 2.5 mg of cagrilintide, 4.5 mg of cagrilintide, 3.0 mg of liraglutide, or a placebo

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Cagrilintide represents the modern re-engineering of that idea: a lipidated, structurally modified amylin analogue stable enough for once-weekly dosing and active at both the amylin and calcitonin receptors