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A novel homozygous disruptive mutation in the SRD5A2-gene in a partially virilized patient with 5alpha-reductase deficiency

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This approach effectively interferes with the body's ability to store lipids, thereby aiding in weight loss [6]

This is when our body is in a glycogen depleted state which allows the body to be in lipogenesis and without the circulation of blood sugar, inhibits muscle breakdown

We thank the Humanized Mouse Platform: Patient Derived Tumor, Gut Microbiota Transplantation and Gene Modification Service at the National Core Facility for Biopharmaceuticals, National Laboratory Animal Center, Taiwan for providing the germ-free mouse facilities