david klow book Clow Inspiration for the Weary Therapist:

ROS and Cardiovascular Diseases The main cardiovascular risk factors, such as hypertension and hypercholesterolemia contribute to enhancing ROS generation, leading to oxidative stress (Li et al., 2014)

(24) in 1992, are activated through a transcription mechanism under hypoxic conditions and then promote the expression of many hypoxia-regulated gene products to form an adaptive mechanism for cell protection

Curr Opin Food Sci 41:159168 Becker K, Mssig-Zufika M, Conrad A, Ldecke A, Schulz C, Seiwert M, Kolossa-Gehring M (2007) German environmental survey for children 2003/06 - KUS - Human biomonitoring of children in Germany

This state of relative hyperglycolysis is facilitated by a hypoxia-induced increase in neuronal GLUT3 [62] and glycolytic enzymes, including pyruvate kinase and hexokinase, the rate-limiting enzymes of glycolysis

in most cases, its used in the medical field