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Search strategy and inclusion criteria Relevant literatures published between 2013 and 2025 were retrieved from PubMed and Web of Science using the following search terms in title field: (Ginsenosides OR Panax OR Ginseng OR Ginseng saponin) AND (Depression OR Depressive disorder OR Depress OR Emotional disorder OR Psychological disorder OR Psychological distress OR Emotional distress OR Emotional stress)